Styrylbenzimidazoles. Synthesis and Biological Activity-Part 3

…, R Loddo, E Marongiu, P La Colla

Index: Vitale, Gabriella; Corona, Paola; Loriga, Mario; Carta, Antonio; Paglietti, Giuseppe; Ibba, Cristina; Giliberti, Gabriele; Loddo, Roberta; Marongiu, Esther; La Colla, Paolo Medicinal Chemistry, 2010 , vol. 6, # 2 p. 70 - 78

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Citation Number: 10

Abstract

As a follow up of an anti-Flaviviridae project, a new series of variously substituted 2-styryl- benzimidazoles were synthesized and tested in vitro for biological activity. Compounds were tested in cell-based assays against viruses representative of: i) two of the three genera of the Flaviviridae family, ie Pestiviruses and Flaviviruses; ii) other RNA virus families, such as Retroviridae, Picornaviridae, Paramyxoviridae, Rhabdoviridae and Reoviridae; iii) two ...