Tetrahedron

New convenient one-step synthesis of 4-arylphthalaz-1-ones

MF Ismail, FA El-Bassiouny, HA Younes

Index: Ismail, M. Fekry; El-Bassiouny, F. A.; Younes, H. A. Tetrahedron, 1984 , vol. 40, # 15 p. 2983 - 2984

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Citation Number: 15

Abstract

4-Arylphthalaz-1-ones (2a–e) are prepared by the hitherto unknown reaction of N- aminophthalimide (1) with aromatic hydrocarbons under Friedel-Crafts conditions. The reaction of N-aminophthalimide with Grignard reagents presents another convenient method for the synthesis of 4-alkyl or 4-arylphthalaz-1-ones.