Molecules

Stereoselective syntheses of fluorescent non-natural aromatic amino acids based on asymmetric Michael additions

H Chen, X Zhong, J Wei

Index: Chen, Heru; Zhong, Xianbin; Wei, Jin Molecules, 2007 , vol. 12, # 5 p. 1170 - 1182

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Citation Number: 7

Abstract

Abstract: Four fluorescent non-natural aromatic amino acids have been synthesized based on a key stereoselective Michael addition reaction. S-1-Phenylethylamine was employed as both the source of amine and the stereoselectivity controller. The overall yields were moderate (30-50%). Fluorescent properties of some of the fluorophores were also investigated. It was found that compounds with a dimethylamino group bonded to the ...