Novel synthesis of angular thiazolo [5, 4-f] and [4, 5-h] quinazolines, preparation of their linear thiazolo [4, 5-g] and [5, 4-g] quinazoline analogs
…, R Guillon, C Lecointe, C Logé, E Chosson, T Besson
Index: Hedou, Damien; Guillon, Remi; Lecointe, Charlotte; Loge, Cedric; Chosson, Elizabeth; Besson, Thierry Tetrahedron, 2013 , vol. 69, # 15 p. 3182 - 3191
Full Text: HTML
Citation Number: 13
Abstract
Synthesis of 9-oxo-8, 9-dihydrothiazolo [5, 4-f] quinazoline-2-carbonitrile (1) or 6-oxo-6, 7- dihydrothiazolo [4, 5-h] quinazoline-2-carbonitrile (2) was reinvestigated with the ambition of varying the position of the thiazole ring linked to the quinazolin-4-one moiety, in order to synthesize two novel linear tricyclic 8-oxo-7, 8-dihydrothiazolo [4, 5-g] quinazoline-2- carbonitrile (3) and 8-oxo-7, 8-dihydrothiazolo [5, 4-g] quinazoline-2-carbonitrile (4). The ...
Related Articles:
[Kreimeyer, Annett; Laube, Bodo; Sturgess, Mike; Goeldner, Maurice; Foucaud, Bernard Journal of Medicinal Chemistry, 1999 , vol. 42, # 21 p. 4394 - 4404]
Hypervalent iodine catalyzed Hofmann rearrangement of carboxamides using oxone as terminal oxidant
[Moriyama, Katsuhiko; Ishida, Kazuma; Togo, Hideo Organic Letters, 2012 , vol. 14, # 3 p. 946 - 949]
[Keenan, Richard M.; Callahan, James F.; Samanen, James M.; Bondinell, William E.; Calvo, Raul R.; Chen, Lichong; DeBrosse, Charles; Eggleston, Drake S.; Haltiwanger, R. Curtis; Hwang, Shing Mei; Jakas, Dalia R.; Ku, Thomas W.; Miller, William H.; Newlander, Kenneth A.; Nichols, Andrew; Parker, Michael F.; Southhall, Linda S.; Uzinskas, Irene; Vasko-Moser, Janice A.; Venslavsky, Joseph W.; Wong, Angela S.; Huffman, William F. Journal of Medicinal Chemistry, 1999 , vol. 42, # 4 p. 545 - 559]
Design and synthesis of N-alkylated saccharins as selective α-1a adrenergic receptor antagonists
[Nerenberg, Jennie B.; Erb, Jill M.; Thompson, Wayne J.; Lee, Hee-Yoon; Guare, James P.; Munson, Peter M.; Bergman, Jeffrey M.; Huff, Joel R.; Broten, Theodore P.; Chang, Raymond S. L.; Chen, Tsing B.; O'Malley, Stacey; Schorn, Terry W.; Scott, Ann L. Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 18 p. 2467 - 2472]
[Hay, Michael P.; Sykes, Bridget M.; Denny, William A.; O'Connor, Charmian J. Journal of the Chemical Society - Perkin Transactions 1, 1999 , # 19 p. 2759 - 2770]