Ring cleavage reactions of 3??and 5??non??substituted isoxazoles

…, AM Gonzalez, D Guerra, FJ Pulido

Index: Alberola, A.; Gonzalez, A. M.; Guerra, D.; Pulido, F. J. Journal of Heterocyclic Chemistry, 1982 , vol. 19, p. 1073 - 1076

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Citation Number: 3

Abstract

Abstract 5-Methylisoxazoles with electron-accepting groups at C-4 (1a-c) and 2, 3- dimethylisoxazolium iodide (II) undergo ring cleavage when treated with organic bases. The nature of the open chain products which were obtained (stable enolates, β-diketones, esters) depends on the group at C-4 and the strength of the base. In some of these processes aromatic aldehydes were used in order to determine the competition between ...

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