Polymetallophilic organic compounds: III. Competitive intramolecular grignard coupling reactions
EL McCaffery, SW Shalaby
Index: McCaffery,E.L.; Shalaby,S.W. Journal of Organometallic Chemistry, 1972 , vol. 44, p. 227 - 231
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Citation Number: 8
Abstract
Abstract Ring formation via an intramolecular Grignard coupling reaction of trihaloalkanes is presented. 2-Methyl-2-(chloromethyl)-l, 5-dichloropentane was prepared and treated with two equivalents of magnesium in tetrahydrofuran, to study the possible ring formation through 1, 5 and/or 1, 3 coupling reactions. A 1, 3 Grignard coupling reaction was shown to occur preferentially, and a cyclopropane derivative was formed. A 1, 5 coupling reaction ...
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