2-Dibenzylaminobutane-1, 4-diol: A versatile intermediate for a chirospecific β-amino acid synthesis
P Gmeiner, F Orecher, C Thomas, K Weber
Index: Gmeiner, Peter; Orecher, Florian; Thomas, Christoph; Weber, Klaus Tetrahedron Letters, 1995 , vol. 36, # 3 p. 381 - 382
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Citation Number: 22
Abstract
Starting from the chiral building block 1, which is readily available from natural aspartic acid, a concise and versatile synthesis of optically active β-amino acids including β-proline derivatives is reported. Regioselective transformations of the 1, 4-bis-electrophile 2 are facilitated by an anchimeric participation.
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