O-TBS-N-tosylhydroxylamine: A reagent for facile conversion of alcohols to oximes
K Kitahara, T Toma, J Shimokawa, T Fukuyama
Index: Kitahara, Katsushi; Toma, Tatsuya; Shimokawa, Jun; Fukuyama, Tohru Organic Letters, 2008 , vol. 10, # 11 p. 2259 - 2261
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Citation Number: 31
Abstract
A variety of oximes were synthesized from the corresponding alcohols, alkyl halides, or alkyl sulfonates without using external oxidants. With this simple two-step procedure involving substitution with readily available TsNHOTBS and subsequent treatment with CsF, a range of oximes were prepared including the ones hardly preparable with conventional procedures.
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