La pronase immobilisée sur poly (N-acryloylpipéridin-4-one): un catalyseur d'hydrolyse L-énantiospécifique des α-aminonitriles

…, L Garrel, F Guillen, H Collet, A Commeyras

Index: Taillades, Jacques; Garrel, Laurence; Guillen, Franck; Collet, Helene; Commeyras, Auguste Bulletin de la Societe Chimique de France, 1995 , vol. 132, p. 119 - 127

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Citation Number: 2

Abstract

Résumé/Abstract α-Aminonitriles are not substrates for pronase (an amidase) in the homogeneous phase but become substrates for pronase when it is immobilized on polymer matrix with ketonic sites (piperidin-4-one). In this paper we show that under low basic aqueous conditions (pH 10-11). the hydration of α-aminonitriles can be efficiently catalyzed by poly (N-acryloylpiperidin-4-one) crosslinked with 1, 4-bis acryloylpiperazine (A (80: 20) ...