Effect of lipophilicity modulation on inhibition of human rhinovirus capsid binders

A Morley, N Tomkinson, A Cook, C MacDonald…

Index: Bioorganic and Medicinal Chemistry Letters, , vol. 21, # 20 p. 6031 - 6035

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Citation Number: 2

Abstract

... Bioorganic & Medicinal Chemistry Letters. ... This lead to the identification of specific structural regions where reduction in polarity can be achieved, so guiding chemistry to analogues with significantly superior profiles to previously reported inhibitors. ...