Carbon monoxide free aminocarbonylation of aryl and alkenyl iodides using DMF as an amide source

K Hosoi, K Nozaki, T Hiyama

Index: Hosoi, Kazushi; Nozaki, Kyoko; Hiyama, Tamejiro Organic Letters, 2002 , vol. 4, # 17 p. 2849 - 2851

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Citation Number: 117

Abstract

In 1974, Heck reported the synthesis of amides from aryl, heterocyclic, and alkenyl halides by the reaction with primary or secondary amines and carbon monoxide catalyzed by Pd species. 2-5 Later, Yamamoto et al. found the double carbonylation of aryl halides afforded α-keto amides and studied comprehensively the mechanistic aspects of both single- and double-carbonylative amide formations. 6,7 Recently, Indolese et al. have reported that ...