A method for the synthesis of unsaturated carbonyl compounds

GM Ksander, JE McMurry…

Index: Ksander,G.M. et al. Journal of Organic Chemistry, 1977 , vol. 42, # 7 p. 1180 - 1185

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Citation Number: 82

Abstract

Decyanation of Acids 10 and 11. To a stirred solution of each acid (100 mg) in dry tetrahydrofuran (3 ml) and redistilled liquid ammonia (30 ml) was added sodium (80 mg) and the stirring was continued for 5 min. An excess of ammonium chloride (2 g) was added in small portions to the reaction mixture and ammonia was allowed to evaporate. The residue was acidified with 10% hydrochloric acid (10 ml) and extracted with ether. The ethereal ...