Design, synthesis, and evaluation of novel A2A adenosine receptor agonists

…, GW Sullivan, J Linden, TL Macdonald

Index: Rieger; Brown; Sullivan; Linden; Macdonald Journal of Medicinal Chemistry, 2001 , vol. 44, # 4 p. 531 - 539

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Citation Number: 105

Abstract

We have been interested in the design, synthesis, and evaluation of novel adenosine A2A agonists. Through the use of comparative molecular field analysis (CoMFA) we have generated a training model that includes 78 structurally diverse A2A agonists and ...