Synthesis and biological evaluation of novel delta (δ) opioid receptor ligands with diazatricyclodecane skeletons

…, P Lazzari, S Ruiu, G Marchese, I Manca…

Index: Loriga, Giovanni; Lazzari, Paolo; Ruiu, Stefania; Marchese, Giorgio; Manca, Ilaria; Casu, Gian Luca; Dessi, Christian; Pinna, Gerard Aime; Asproni, Battistina; Murineddu, Gabriele European Journal of Medicinal Chemistry, 2013 , vol. 69, p. 413 - 426

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Citation Number: 4

Abstract

Abstract Considering the interesting pharmacological profile of the delta (δ) selective opioid agonist compound SNC-80, conformationally constrained analogs containing two diazatricyclodecane ring systems in place of dimethylpiperazine core motif were synthesized.

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