Azomethine ylide cycloaddition/reductive heterocyclization approach to oxindole alkaloids: asymmetric synthesis of (-)-horsfiline

G Cravotto, GB Giovenzana, T Pilati…

Index: Grochowski,E.; Eckstein,Z. Bulletin de l'Academie Polonaise des Sciences, Serie des Sciences Chimiques, 1963 , vol. 11, # 8 p. 443 - 446

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Citation Number: 125

Abstract

... This finding brought out the potential of the two-step cycloaddition/reductive heterocyclization protocol for the enantioselective synthesis of (−)-horsfiline 1 (Scheme 2). Toward this end, a series of esters and amides 9c−g bearing a ... entry a, chiral auxiliary, yield, % b, de c. ... 3, e, 63, 16 ...