Tetrahedron

Total synthesis of (±)-stemonamide and (±)-isostemonamide

AS Kende, JIM Hernando, JBJ Milbank

Index: Kende, Andrew S; Martin Hernando, Jose I; Milbank, Jared B.J Tetrahedron, 2002 , vol. 58, # 1 p. 61 - 74

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Citation Number: 63

Abstract

Two different approaches to the alkaloids stemonamide and isostemonamide using N- acyliminium chemistry are described. The approach using an aldol spirocyclization to construct the second contiguous spirocenter was successful. The total synthesis of these ...