Chemistry letters

N-hydroxysuccinimide-promoted oxidation of primary alcohols and aldehydes to form active esters with hypervalent (III) iodine

N Wang, R Liu, Q Xu, X Liang

Index: Wang, Naiwei; Liu, Renhua; Xu, Qing; Liang, Xinmiao Chemistry Letters, 2006 , vol. 35, # 6 p. 566 - 567

Full Text: HTML

Citation Number: 11

Abstract

A simple, mild, and efficient method for the conversion of primary alcohols and aldehydes to N-hydroxysuccinimide esters with (diacetoxyiodo) benzene in high yield is developed. N- Hydroxysuccinimide acts not only as an esterification partner but also as an activator of PhI (OAc) 2 in this reaction.

Related Articles:

Preparation of N-hydroxysuccinimido esters via palladium-catalyzed carbonylation of aryl triflates and halides

[Lou, Rongliang; VanAlstine, Melissa; Sun, Xufeng; Wentland, Mark P. Tetrahedron Letters, 2003 , vol. 44, # 12 p. 2477 - 2480]

Convenient Synthesis of N-Hydroxysuccinimide Esters from Carboxylic Acids Using Triphosgene

[Kim, Misoo; Han, Ki-Jong Synthetic Communications, 2009 , vol. 39, # 24 p. 4467 - 4472]

Synthesis of procainamide metabolites. N-acetyl desethylprocainamide and desethylprocainamide

[Adamczyk, Maciej; Fino, James R. Organic Preparations and Procedures International, 1996 , vol. 28, # 4 p. 470 - 474]

More Articles...