Tetrahedron Letters

Facile lipase catalysed syntheses of (S)-(+)-4-hydroxy-β-ionone and (S)-(+)-4-hydroxy-β-damascone: chiral flavorants and synthons

GP More, SV Bhat

Index: More, Gauri P.; Bhat, Sujata V. Tetrahedron Letters, 2013 , vol. 54, # 32 p. 4148 - 4149

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Citation Number: 5

Abstract

Enantioselective syntheses of (S)-(+)-4-hydroxy-β-ionone and (S)-(+)-4-hydroxy-β- damascone have been achieved through pig pancreatic lipase catalysed trans-esterification. These molecules find utility as constituent in fruit-type fragrance and flavor formulations and as chiral synthons in asymmetric synthesis of bioactive terpenoids.