Synlett

Syntheses of N-Alkylated Carbazolones via Pd (OAc) 2-Mediated Intramolecular Coupling of N-Substituted 3-(Arylamino) cyclohex-2-enones

W Bi, X Yun, Y Fan, X Qi, Y Du, J Huang

Index: Bi, Wenying; Yun, Xiliu; Fan, Yanfeng; Qi, Xiuxiang; Du, Yunfei; Huang, Jianhui Synlett, 2010 , # 19 p. 2899 - 2904

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Citation Number: 5

Abstract

Abstract A variety of functionalized N-alkylated carbazolones were prepared via N-alkylation of 3-(arylamino) cyclohex-2-enones followed by an intramolecular oxidative coupling mediated by Pd (OAc) 2 under an oxygen atmosphere. This approach adopts an inverted sequence, consisting of the conventional annulation and subsequent N-alkylation.

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