Asymmetric synthesis of (1S, 2R)-(+)-2-phenyl-1-aminocyclopropane-1-carboxylic acid
RM Williams, GJ Fegley
Index: Williams, Robert M.; Fegley, Glenn J. Journal of Organic Chemistry, 1993 , vol. 58, # 24 p. 6933 - 6935
Full Text: HTML
Citation Number: 27
Abstract
The synthesis of both the (E)-and (2)-isomers of the unnatural amino acid, 2-phenyl-l- aminocyclopropane-l-carboxylic acid (cyclopropylPhe, Figure 11, has been accomplished in racemic fashion.'To date, only (2)-cyclopropylPhe has been synthesized in diastereoenriched form; 2 (E)-and (2)-cyclopropylPhe have been resolved via the agency of (-)-brucine: and (-)-0, O-dibenzoyltartaric acid,'respectively. In recent years there has been ...
Related Articles:
[Davies, Huw M. L.; Bruzinski, Paul R.; Lake, Debra H.; Kong, Norman; Fall, Michael J. Journal of the American Chemical Society, 1996 , vol. 118, # 29 p. 6897 - 6907]
[Davies, Huw M. L.; Bruzinski, Paul R.; Lake, Debra H.; Kong, Norman; Fall, Michael J. Journal of the American Chemical Society, 1996 , vol. 118, # 29 p. 6897 - 6907]
[Davies, Huw M. L.; Bruzinski, Paul R.; Lake, Debra H.; Kong, Norman; Fall, Michael J. Journal of the American Chemical Society, 1996 , vol. 118, # 29 p. 6897 - 6907]
[Davies, Huw M. L.; Bruzinski, Paul R.; Lake, Debra H.; Kong, Norman; Fall, Michael J. Journal of the American Chemical Society, 1996 , vol. 118, # 29 p. 6897 - 6907]
[Davies, Huw M. L.; Bruzinski, Paul R.; Lake, Debra H.; Kong, Norman; Fall, Michael J. Journal of the American Chemical Society, 1996 , vol. 118, # 29 p. 6897 - 6907]