Synthesis and Anti??tumor Activities of Novel Pyrazolo [1, 5??a] pyrimidines

…, YF Zhao, XL Zhao, XY Yuan, P Gong

Index: Li, Juan; Zhao, Yan Fang; Zhao, Xiang Lin; Yuan, Xiao Ye; Gong, Ping Archiv der Pharmazie, 2006 , vol. 339, # 11 p. 593 - 597

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Citation Number: 53

Abstract

Abstract A series of novel pyrazolo [1, 5-a] pyrimidines were designed and synthesized in order to find novel potent anti-tumor compounds. The structures of all the compounds were confirmed by IR, 1 H-NMR, elemental analysis, and MS. Their anti-tumor activities against cancer cell lines were tested by the MTT method in vitro. Compound 19 displayed potent anti- tumor activity.

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