Hydroxyl substitutional effect on selective synthesis of cis, trans stilbenes and 3-arylcoumarins through Perkin condensation

CF Xiao, Y Zou, JL Du, HY Sun…

Index: Xiao, Chun-Fen; Zou, Yong; Du, Jian-Li; Sun, Hong-Yi; Liu, Xian-Ke Synthetic Communications, 2012 , vol. 42, # 9 p. 1243 - 1258

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Citation Number: 13

Abstract

The remarkable medical importance and the scarcity in nature of polyphenolic stilbenes prompted studies for their synthesis. The protocols for establishing ethene bridge between the two phenyl rings are mainly associated with diverse reactions, such as the Wittig reaction, [ 10 10. Pettit , GR ; Singh , SB ; Boyd , MR ; Hamel , E. ; Pettit , RK ; Schmidt , JM ; Hogan , F. Antineoplastic agents, 291: Isolation and synthesis of combretastatins A-4, A-5, and A-6 . J. Med. Chem. ...