A convergent approach to 2-substituted-5-methoxyindoles. Application to the synthesis of melatonin
B Quiclet-Sire, B Sortais, SZ Zard
Index: Quiclet-Sire, Beatrice; Sortais, Benoit; Zard, Samir Z. Chemical Communications, 2002 , # 16 p. 1692 - 1693
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Citation Number: 19
Abstract
The indole nucleus is a key structural feature in a large number of alkaloids and related compounds, many of which exhibit a potent pharmacological activity. 1 It is not therefore surprising that numerous routes have been devised over the years to construct the indole ring. 2 In the present communication, we describe a simple approach to 2-substituted-5- methoxyindoles and its application to the synthesis of melatonin, a hormone mainly ...
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