Tetrahedron Letters
Remarkable catalytic activity of silica nanoparticle in the bis-Michael addition of active methylene compounds to conjugated alkenes
S Banerjee, S Santra
Index: Banerjee, Subhash; Santra, Swadeshmukul Tetrahedron Letters, 2009 , vol. 50, # 18 p. 2037 - 2040
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Citation Number: 49
Abstract
We have demonstrated the remarkable catalytic activity of silica nanoparticles (NPs) in the unusual bis-Michael addition of active methylene compounds to conjugated alkenes at room temperature. The catalyst silica NPs were reused up to seven runs without appreciable loss of catalytic activity.
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