Selective sp3 C–H Bond Activation Based on a Carbocation Relay: Friedel–Crafts Reaction with Alkanes as the Alkylating Component

J Wang, P Zhou, Y Wang

Index: Wang, Jie; Zhou, Pengfei; Wang, Yang European Journal of Organic Chemistry, 2011 , # 2 p. 264 - 270

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Citation Number: 2

Abstract

Abstract A highly efficient and selective intramolecular Friedel–Crafts reaction of 3- methylbutyl or 4-methylpentyl-substituted aromatics has been developed using a carbocation relay strategy through selective sp 3 C–H bond activation, providing a facile and cost-effective approach for the construction of benzocyclic compounds. A variety of 1, 1- dimethylindane and naphthalene derivatives have been prepared from very simple ...

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