The Journal of Organic Chemistry

Analogs of phosphoenolpyruvate. 4. Syntheses of some new vinyl-and methylene-substituted phosphonate derivatives

RM Davidson, GL Kenyon

Index: Davidson, Robert M.; Kenyon, George L. Journal of Organic Chemistry, 1980 , vol. 45, # 13 p. 2698 - 2703

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Citation Number: 11

Abstract

PEP 1 substrate in the enolase rea~ tion~,~ and to serve as a weak competitive inhibitclr of rabbit muscle pyruvate kina~ e.~ Later, in 1976, Davidson and Kenyon reported some new synthetic approaches to 1 and made unambiguous assignments of the vinyl protons in its NMR spectrum. l In this paper, we report the preparation of a series of substituted analogules of PEP which, by virtue of being geometrically defined and conformationally ...