4-Iodophenylcholine: a potential myocardial imaging agent

DH Hunter, YZ Ponce, GW Brown…

Index: Hunter; Zea Ponce; Brown; et al. Canadian Journal of Chemistry, 1984 , vol. 62, # 10 p. 2015 - 2018

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Citation Number: 10

Abstract

The compound O-(4-iodophenyl) choline iodide has been synthesized using iodine-125, iodine-127, and iodine-131 by diazonium salt and melt exchange procedures. Radiochemical yields of approximately 2% and 56%, respectively, were obtained. The biodistribution of this compound in mice was analyzed in order to determine its potential as a myocardial imaging agent. Selective myocardial concentration was observed at 5 min post ...