Iron-oxide nanoparticles mediated cyclization of 3-(4-chlorophenyl)-1-hydrazinylisoquinoline to 1-(4, 5-dihydropyrazol-1-yl) isoquinolines

…, P Manivel, K Prabakaran, JS Jin, ED Jeong…

Index: Nawaz Khan; Manivel; Prabakaran; Jin, Jong Sung; Jeong, Euh Duck; Kim, Hyun Gyu; Maiyalagan Research on Chemical Intermediates, 2012 , vol. 38, # 2 p. 571 - 582

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Citation Number: 6

Abstract

Abstract Iron-oxide nanoparticles were obtained using chitosan templates and their crystalline character and particle size have been confirmed through powder x-ray diffraction and transmission electron microscopy measurements. The particle sizes were found to be 10–25 nm. The diversified chalcones 2 were reacted with 1-hydrazinylisoquinoline 1 in the presence of iron-oxide nanoparticles to the corresponding pyrazolines 3a–j in high yield ...