Preparation of Fused Tetracyclic Quinazolinones by Combinations of Aza??Wittig Methodologies and CuI??Catalysed Heteroarylation Processes
…, PM Fresneda, R Orenes, P Molina
Index: Bleda, Juan Antonio; Fresneda, Pilar M.; Orenes, Raul; Molina, Pedro European Journal of Organic Chemistry, 2009 , # 15 p. 2490 - 2504
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Citation Number: 14
Abstract
Abstract A number of linear quinazolinones fused to five-membered rings–benzimidazo [2, 1- b] quinazolinones 8 and benzothiazolo [2, 3-b] quinazolinones 10–have been prepared from iminophosphoranes 4, derived from N-substituted o-azidobenzamides by a combination of the aza-Wittig methodology and Cu I-catalysed heteroarylation. The presence of a nitrogen functionality in the N-aryl substituent of 4 promotes heterocyclization after an aza-Wittig ...
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