Intramolecular participation by a neighboring amide group in the hydrolysis of N-acylimidazoles
RL Kogan, TH Fife
Index: Kogan, Robert L.; Fife, Thomas H. Journal of Organic Chemistry, 1984 , vol. 49, # 26 p. 5229 - 5232
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Citation Number: 12
Abstract
Results In Figures 1 and 2 plots of log ko vs. pH are shown for the disappearance of N-(P- phenylpropiony1) imidazole and N-isovalerylimidazole at 30" C in H20 (H= 0.1 M). Hydronium ion, hydroxide ion, and water-catalyzed reactions can be observed. The equation for ko is given in eq 1, where K, is the dissociation constant of the N-acyl-
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