Russian Journal of Bioorganic Chemistry

The synthesis of N 2, N 6-substituted diaminopurine ribosides

NA Golubeva, AV Shipitsyn

Index: Golubeva; Shipitsyn Russian Journal of Bioorganic Chemistry, 2007 , vol. 33, # 6 p. 562 - 568

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Abstract

Abstract A series of new 2, 6-substituted diaminopurine riboside derivatives were synthesized by activation of protected xantosine with sulfonyl chlorides followed by treatment with various amines. The relationship between the reactivity of intermediates and the nature of the activating agents was studied.