An efficient multicomponent and stereoselective synthesis of new spiro [indeno [1, 2??b] quinoxaline??11, 2′??pyrrolidine] derivatives

M Moemeni, H Arvinnezhad, S Samadi…

Index: Moemeni, Mehdi; Arvinnezhad, Hamid; Samadi, Saadi; Tajbakhsh, Mahmood; Jadidi, Khosrow; Khavasi, Hamid Reza Journal of Heterocyclic Chemistry, 2012 , vol. 49, # 1 p. 190 - 194

Full Text: HTML

Citation Number: 11

Abstract

Abstract New spiro [indeno [1, 2-b] quinoxaline-11, 2′-pyrrolidine] derivatives were prepared in high yield stereoselectively from an efficient multicomponent 1, 3-dipolar cycloaddition reaction between ninhydrin, phenylenediamine, sarcosine, and chalcones. The regiochemistry and stereochemistry of resultant cycloadducts have been determined by several 2D NMR spectroscopic techniques and X-ray single crystal diffraction. J. ...