Neurotropic and psychotropic compounds. XLVI. Several derivatives of cyclohexylphenyl sulfide

JO Jílek, J Holubek, J Pomykáček…

Index: Jilek,J.O. et al. Collection of Czechoslovak Chemical Communications, 1971 , vol. 36, p. 2824 - 2830

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Abstract

Neurotropic and Psychotropic Substances. XLVI. 2825 an aqueous-ethanolic solution of potassium hydroxide. During subsequent acidification thiophenol appeared so that, in addition to hydrolysis and decarboxylation, the cyc! ohexyl-S bond is also cleaved. The acid was obtained in only a 19% yieldaccording to its NMR spectrum it is 2-(phenylthio) cyclohexene-l~ acetic acid (IX). The attempt at cyclization of acid IX with polyphosphoric ...