Journal of the American Chemical Society

Chemotherapeutic Nitrofurans. III. 1 N-(5-Nitro-2-furfurylidene)-3-aminotetrahydro-1, 3-oxazine-2-one

K Hayes

Index: Hayes Journal of the American Chemical Society, 1955 , vol. 77, p. 2333

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Citation Number: 2

Abstract

Replacement of the tertiary bases by calcium oxide or potassium hydroxide (in benzene) gave unsatisfactory results; in the latter case 11% of impure protoanemonin was obtained. The dichlorovalerolactone, unlike the dibromide, is difficult to prepare, as addition of chlorine to the a-apgelica lactone (11) always is accompanied by substitution. The dichlorolactone yielded with tertiary amines only an unsaturated monochlorolactone, probably analogous ...