Synlett

New Methodology for the Synthesis of 3-Substituted Coumarins via Palladium-Catalyzed Site-Selective Cross-Coupling Reactions

S Martins, PS Branco, C María, MA Sierra, A Pereira

Index: Martins, Sergio; Branco, Paula S.; Delatorre, Maria C.; Sierra, Miguel A.; Pereira, Antonio Synlett, 2010 , # 19 p. 2918 - 2922

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Citation Number: 16

Abstract

Abstract A particularly useful, easy, and concise synthesis of diversified 3-aryl coumarin was achieved using Heck coupling reactions between coumarin and aryliodides. The introduction of the aryl moiety occurred regioselective at the 3-position of the heteroaromatic ring.

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