On the binding site of quinolone antibacterials. An attempt to probe the shen model

S Hanessian, R Saladino, JC Nunez

Index: Hanessian, Stephen; Saladino, Raffaele; Nunez, Jose Cid Bioorganic and Medicinal Chemistry Letters, 1996 , vol. 6, # 19 p. 2333 - 2338

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Citation Number: 7

Abstract

Download full text in PDF Opens in a new window. Article suggestions will be shown in a dialog on return to ScienceDirect. ... Please enable JavaScript to use all the features on this page. ... Quinolone-nucleic acid base hybrids were synthesized in an effort to probe a mechanistic model and a proposed mode of antibacterial action where stacked pairs of quinolones interact with DNA through H-bonding. ... Quinolone-nucleic acid base hybrids were synthesized in an ...