General Ambient Temperature Benzylic Metalations Using Mixed-Metal Li/K-TMP Amide

A Manvar, P Fleming, DF O'Shea

Index: Blangetti, Marco; Fleming, Patricia; O'Shea, Donal F. Beilstein Journal of Organic Chemistry, 2011 , vol. 7, art. no. 145, p. 1249 - 1254

Full Text: HTML

Citation Number: 3

Abstract

Highly regioselective benzylic metalations in hydrocarbon solvent have been achieved at rt and 0° C using a mixed-metal Li/K-TMP amide comprised of KO t Bu, BuLi, and 2, 2, 6, 6,- tetramethylpiperidine (TMP (H)). Mixing of KO t Bu, BuLi, and TMP (H) in heptane gave a

Related Articles:

Oxidative phosphonylation of aromatic compounds

[Effenberger, Franz; Kottmann, Hariolf Tetrahedron, 1985 , vol. 41, # 19 p. 4171 - 4182]

Photochemical oxidation and dimerization of alkylbenzenes. Selective reactions of the alkyl side groups

[Pasternak, Mordechai; Morduchowitz, Abraham Tetrahedron Letters, 1983 , vol. 24, # 40 p. 4275 - 4278]

Studies in azide chemistry. Part 13 [1]. Intermolecular insertion of azide-derived polyfluorinated aryl-and heteroaryl-nitrenes into ring C H bonds of 1, 3, 5-trimethyl- …

[Banks,R.E.; Madany,I.M. Journal of Fluorine Chemistry, 1985 , vol. 30, p. 211]

Intermolecular aromatic substitution by aryl nitrenes

[Abramovitch,R.A. et al. Journal of Organic Chemistry, 1972 , vol. 37, # 17 p. 2705 - 2710]

The role of aroyloxyl radicals in the formation of solvent-derived products in photodecomposition of diaroyl peroxides. The reactivity of substituted cyclohexadienyl …

[Takahara, Shigeru; Urano, Tishiyuki; Kitamura, Akihide; Sakuragi, Hirochika; Kikuchi, Osamu; et al Bulletin of the Chemical Society of Japan, 1985 , vol. 58, # 2 p. 688 - 697]

More Articles...