Quinazolines. V. Synthesis and proof of structure of 1, 3-diamino-5, 6-dihydrobenzo [f] quinazoline

EP Burrows, A Rosowsky…

Index: Burrows,E.P. et al. Journal of Organic Chemistry, 1967 , vol. 32, p. 4090 - 4092

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Citation Number: 13

Abstract

(4) Our rationale for the design of bridged pyrimethamine analogs, of which 1 is only one example. was first presented in connection with the synthesis of fully aromatic l, 3- diaminobenso [flquinazolines;~ cf. EJ Modest, A. Rosowsky, S. Farber, and GE Foley, Abstracts of Papers, Ninth International Cancer Congress, Tokyo, Japan, October 24, 1966, p 325. The same concept has been invoked recently by Taylor and co-workers in their ...