Glycerol/CuI/Zn as a recyclable catalytic system for synthesis of vinyl sulfides and tellurides

…, DB Lima, PMY Borba, G Perin, D Alves, RG Jacob…

Index: Goncalves, Loren C.C.; Lima, David B.; Borba, Pedro M.Y.; Perin, Gelson; Alves, Diego; Jacob, Raquel G.; Lenardao, Eder J. Tetrahedron Letters, 2013 , vol. 54, # 26 p. 3475 - 3480

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Citation Number: 12

Abstract

A convenient approach to the Cu-catalyzed coupling of diphenyl disulfide and diphenyl ditelluride with vinyl bromides using a recyclable catalytic system and glycerol as a green solvent is described. This protocol was efficiently used in the preparation of vinyl sulfides and vinyl tellurides with a variety of substituents in good yields and stereoselectively. The solvent/catalyst system was directly reused for four cycles without loss of activity.