Journal of Chemical Research, Synopses

Studies on Pyrazines. Part 33.1 Synthesisof 2, 3-Diaminopyrazines via [1, 2, 5] Thiadiazolo [3, 4-b] pyrazines

N Sato, H Mizuno

Index: Sato, Nobuhiro; Mizuno, Hajime Journal of Chemical Research - Part S, 1997 , # 7 p. 250 - 251

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Citation Number: 2

Abstract

The syntheses of [1,2,5]thiadiazolo[3,4-b]pyrazine (3) and its methyl and/or phenyl derivatives as well as their reduction to 2,3-diaminopyrazines 4 are described. ... The cleavage of fused pyrazines represents a useful method for the synthesis of substituted pyrazines.2 We have pre- viously reported the synthesis of 2,3-diaminopyrazines via hydrogenolysis of furazano[3,4-b]pyrazines which were pre- pared by the condensation of ...