Cyclization Studies in the Syntheses of Methoxy-Substituted 1-Phenyl-4-hydroxy-2-naphthoic Acids. III. 1

LH Klemm, EP Antoniades, CD Lind

Index: Klemm,L.H. et al. Journal of Organic Chemistry, 1962 , vol. 27, p. 519 - 526

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Citation Number: 18

Abstract

The Stobbe t-butyl half esters from 3-methoxy-, 3, 3'-dimethoxy-, 3, 4, 3', 4'-tetramethoxy-, and 3, 4, 5, 3', 4'-pentamethoxy-benzophenones were cyclized (and subsequently hydrolyzed) to methoxy-substituted t-butyl l-phenyl-4-hydroxy-2-naph-thoates by heating with anhydrous sodium acetate in acetic anhydride. Complete product analyses were made on the reaction mixtures based on selective alkaline extractions of the various acidic ...