Selective alkylations of 1, 4: 3, 6-dianhydro-d-glucitol (isosorbide)

…, L Munnier, R Tamion, F Marsais, G Queguiner

Index: Abenhaiem, D.; Loupy, A.; Munnier, L.; Tamion, R.; Marsais, F.; Queguiner, G. Carbohydrate Research, 1994 , vol. 261, # 2 p. 255 - 266

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Citation Number: 63

Abstract

Abstract Each of the two hydroxyl groups of isosorbide can be alkylated selectively, either by direct alkylation with benzyl chloride or allyl bromide according to the reaction conditions, or by a three-step procedure involving selective monoacetylation, alkylation with four different reagents, and finally deacetylation. Monobutyl and monomethyl derivatives from isosorbide are also described.