Asymmetric 1, 2-Perfluoroalkyl Migration: Easy Access to Enantioenriched α-Hydroxy-α-perfluoroalkyl Esters

P Wang, LW Feng, L Wang, JF Li, S Liao…

Index: Wang, Pan; Tao, Wen-Jie; Sun, Xiu-Li; Liao, Saihu; Tang, Yong Journal of the American Chemical Society, 2013 , vol. 135, # 45 p. 16849 - 16852

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Citation Number: 10

Abstract

This study has led to the development of a novel, highly efficient, 1, 2-perfluoro-alkyl/-aryl migration process in reactions of hydrate of 1-perfluoro-alkyl/-aryl-1, 2-diketones with alcohols, which are promoted by a Zn (II)/bisoxazoline and form α-perfluoro-alkyl/-aryl- ...