Effect of structural modifications in the C7-C11 region of the retinoid skeleton on biological activity in a series of aromatic retinoids
MI Dawson, PD Hobbs, KA Derdzinski…
Index: Dawson; Hobbs; Derdzinski; Chao; Frenking; Loew; Jetten; Napoli; Williams; Sani; Wille Jr.; Schiff Journal of Medicinal Chemistry, 1989 , vol. 32, # 7 p. 1504 - 1517
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Citation Number: 39
Abstract
A series of conformationally restricted analogues of (E)-4-[2-(5, 6, 7, 8-tetrahydro-5, 5, 8, 8- tetramethyl-2-naphthalenyl) propenyl] benzoic acid-(E)-4-[1-(5, 6, 7, 8-tetrahydro-5, 5, 8, 8- tetramethyl-2-naphthalenyl)-2-propenyl] benzoic acid,(E)-4-[3-(5, 6, 7, 8-tetrahydro-5, 5, 8, 8- tetramethyl-2-naphthalenyl)-2-buten-2-y1] benzoic acid, trans-4-[2-(5, 6, 7, 8-tetrahydro-5, 5, 8, 8-tetramethyl-2-naphthalenyl) cyclopropyl] benzoic acid, 4-(5, 6, 7, 8-tetrahydro-5, 5, 8, ...
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