Tetrahedron letters

A one-pot procedure for the synthesis of alkynes and bromoalkynes from aldehydes

P Michel, D Gennet, A Rassat

Index: Michel, Patrick; Gennet, Dominique; Rassat, Andre Tetrahedron Letters, 1999 , vol. 40, # 49 p. 8575 - 8578

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Citation Number: 81

Abstract

Alkynes RC CH were obtained in good yield through a one-pot procedure by a sequence of reactions starting from a Wittig-type condensation of the aldehydes RCHO with the ylide derived from dibromomethyltriphenylphosphonium bromide 5. The same reactions could also be used to prepare the intermediate dibromoalkenes RCH CBr2, and in certain cases, the bromoalkynes RC CBr.

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