Synthesis of asymmetric iron–pybox complexes and their application to aziridine forming reactions

M Redlich, MM Hossain

Index: Redlich, Mark; Hossain, M. Mahmun Tetrahedron Letters, 2004 , vol. 45, # 49 p. 8987 - 8990

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Citation Number: 62

Abstract

The synthesis of a series of iron–pybox complexes and their employment in the catalytic asymmetric aziridine forming reaction is presented. When AgSbF6 is used as an initiator, the i-pr-and t-bu-pybox complexes produce 47% of the cis-aziridine in moderate ee's with the bulk of side products consisting of the trans-isomer and β-amino-α, β-unsaturated esters (AUE's).