A new strategy for the enantioselective synthesis of carba-prostacyclin analogues based on organocopper conjugate addition to a bicyclic azoene and its application …

M van Bergen, HJ Gais

Index: Journal of the American Chemical Society, , vol. 124, # 16 p. 4321 - 4328

Full Text: HTML

Citation Number: 18

Abstract

... Journal of the ... 2002, 124 (16), pp 4321–4328. DOI: 10.1021/ja0125772. Publication Date (Web): March 29, 2002. Copyright © 2002 American Chemical Society. ... Because of the inherent chemical and metabolic instability of prostacyclin, which is mainly due to the ring O-atom and ...