Design, synthesis and biological evaluation of organophosphorous-homodimers as dual binding site acetylcholinesterase inhibitors

R Xie, Q Zhao, T Zhang, J Fang, X Mei, J Ning…

Index: Bioorganic and Medicinal Chemistry, , vol. 21, # 1 p. 278 - 282

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Citation Number: 12

Abstract

... Bioorganic & Medicinal Chemistry. ... In short, the yield up to 90% was achieved by setting the suitable temperature, selecting the correct chemical addition order, taking the optimal reactant ratio, and reacting over an appropriate time of period. ...