Tetrahedron

Copper (II) in organic synthesis. XI. Evaluation of the ligand architecture on the efficiency of a copper (II) catalyst for enantioselective Michael reactions

G Desimoni, G Dusi, G Faita, P Quadrelli, PP Righetti

Index: Desimoni, Giovanni; Dusi, Guglielmo; Faita, Giuseppe; Quadrelli, Paolo; Righetti, PierPaolo Tetrahedron, 1995 , vol. 51, # 14 p. 4131 - 4144

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Citation Number: 46

Abstract

Several bis-copper (II) complexes with chiral ligands derived from 2-substituted 2- (salicylideneamino) ethanols have been tested as catalysts of enantioselective Michael reactions. The degree of enantioselection is strongly affected by the architecture of the ligand. The best result (75% ee) was obtained for a ligand having a substituent potentially suitable to induce the formation of a bis-tetradentate copper (II) complex with a square ...