Synthesis and photochemistry of a new photolabile derivative of GABA-neurotransmitter release and receptor activation in the microsecond time region

KR Gee, R Wieboldt, GP Hess

Index: Gee, Kyle R.; Wieboldt, Raymond; Hess, George P. Journal of the American Chemical Society, 1994 , vol. 116, # 18 p. 8366 - 8367

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Citation Number: 71

Abstract

Rapid release of biologically active molecules from photolabile, or" caged", precursors is an important technique in the study of fast biological processes.'Photolysis of caged compounds provides temporal and spatial control of the distribution of substrate concentration in systems where diffusional mixing delays are a barrier to observation of rapid events. The most widely used caging group is the o-nitrobenzyl group. o-Nitrobenzyl ...